Gestational history in cases of non-syndromic unilateral cleft lip and palate: a retrospective study (2017)
- Authors:
- Autor USP: NEVES, LUCIMARA TEIXEIRA DAS - FOB
- Unidade: FOB
- Subjects: FISSURA LÁBIOPALATINA; ANOMALIA CRANIOFACIAL; COMPLICAÇÕES NA GRAVIDEZ
- Language: Inglês
- Abstract: Aim: Cleft lip and palate (CLP) is the most common congenital craniofacial anomaly, beingconsidered as a public health problem by the WHO. Clefts can be syndromic, being part ofsyndromes, or non-syndromic, when occurring as an independent phenotype, correspondingto approximately 70% of CLP cases. Non-syndromic clefts present multifactorial etiology,which is associated with genetic and environmental factors. Taking into account theenvironmental aspects and risk factors for clefts, the aim of this exploratory study was toinvestigate gestational history in cases of non-syndromic unilateral cleft lip and palate.Methods and results: The following data were analyzed: maternal age at conception, prenatalcare and pregnancy complications in 105 records of patients with non-syndromic unilateralcleft lip and palate admitted at the Hospital for Rehabilitation of Craniofacial Anomalies(HRAC-USP). The average maternal age at conception was 26 years old, with variationbetween 17 and 47 years old. Only 69 records presented information regarding prenatalcare, among which 91.3% of mothers had prenatal checkups done. Pregnancy intercurrencewas shown in 32% of 72 cases that presented this information, being infections the mostcommon. The use of medications such as antibiotics, antiemetics and analgesics was foundin 54% of 54 cases in which this information was described. Conclusions: In this sample,relevant data in the gestational history were found regarding pregnancy intercurrence,specifically the occurrence of infections and use of medications.
- Imprenta:
- Publisher: Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo
- Publisher place: Bauru
- Date published: 2017
- Source:
- Título do periódico: Anais
- Conference titles: Simpósio Internacional de Fissuras Orofaciais e Anomalias Relacionadas
-
ABNT
PEREIRA, Maria Carolina de Moraes et al. Gestational history in cases of non-syndromic unilateral cleft lip and palate: a retrospective study. 2017, Anais.. Bauru: Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, 2017. Disponível em: https://repositorio.usp.br/directbitstream/2e95fbc0-1ae3-4fe6-876c-31a5ac9aca3f/2940117.pdf. Acesso em: 04 jun. 2024. -
APA
Pereira, M. C. de M., Garbieri, T. F., Mateo-Castillo, J. F., & Neves, L. T. das. (2017). Gestational history in cases of non-syndromic unilateral cleft lip and palate: a retrospective study. In Anais. Bauru: Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo. Recuperado de https://repositorio.usp.br/directbitstream/2e95fbc0-1ae3-4fe6-876c-31a5ac9aca3f/2940117.pdf -
NLM
Pereira MC de M, Garbieri TF, Mateo-Castillo JF, Neves LT das. Gestational history in cases of non-syndromic unilateral cleft lip and palate: a retrospective study [Internet]. Anais. 2017 ;[citado 2024 jun. 04 ] Available from: https://repositorio.usp.br/directbitstream/2e95fbc0-1ae3-4fe6-876c-31a5ac9aca3f/2940117.pdf -
Vancouver
Pereira MC de M, Garbieri TF, Mateo-Castillo JF, Neves LT das. Gestational history in cases of non-syndromic unilateral cleft lip and palate: a retrospective study [Internet]. Anais. 2017 ;[citado 2024 jun. 04 ] Available from: https://repositorio.usp.br/directbitstream/2e95fbc0-1ae3-4fe6-876c-31a5ac9aca3f/2940117.pdf - Triagem de mutação no éxon 3 do gene IRF6 em indivíduos com fissura labiopalatina e agenesia dentária: padronização de protocolo para seqüenciamento de DNA genômico a partir de saliva
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